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文献和实验中科院高福院士课题组 2020 年发表了哪些重要的研究成果?
抗体的主要靶标。2020 年 3 月 11 日,高福院士联合逯光文在 Cell Host & Microbe 发文:Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody。该研究报告了狂犬病毒 RABV-G 的晶体结构,分别在〜pH-8.0 时以游离形式和在〜pH-6.5 时与中和
Identification of Legionella in Clinical Samples
, although this test is limited to L. pneumophila serogroup 1 (Lp1) (Helbig et al., J Clin Microbiol 41:838–840, 2003). The use of molecular techniques can improve Legionaire’s disease (LD) diagnosis by detecting other serogroups and species (Diederen et al., J Clin
for reporting both protein native mobility and binding specificity. Immunosubtraction is performed by removing antibody-bound target proteins from electrophoretic detection via a size-based exclusion filter, while unbound nontarget
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