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文献和实验Chemical Mutational Analysis of Glucocorticoid Receptor
This chapter describes a chemical method for mutational analysis of the human glucocorticoid receptor (hGR) cDNA. Corticosteroid-resistant (CR) asthma is associated with in vitro and in vivo defects in mononuclear cell function
在肾上腺皮质激素中,与糖质代谢有关的类固醇激素的总称。以皮质(甾)醇,皮质(甾)酮等为代表。此激素可提高肝的糖原和血糖值,促进从蛋白质合成糖质。此激素的生成可受脑下垂体分泌的副肾皮质激素调节。
High-Yield Purification of Functionally Active Glucocorticoid Receptor
The glucocorticoid receptor (GR) resides in the cytoplasm as a complex with chaperones. Upon ligand association, GR shuttles into the nucleus, and binds to its hormone response elements to control expression of particular genes
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