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文献和实验Production of Human Antibodies from Transgenic Mice
4. the human heavy-chain transgene contains, at minimum, the majority of the human VH genes, all the D genes, all the JH genes, Cμ Cδ , and at least one Cγ gene, together with regulatory elements
Preparation of Defined Human Embryonic Stem Cell Populations for Transcriptional Profiling
., Johnstone, S.E., Levine, S.S., Zucker, J.P., Guenther, M.G., Kumar, R.M., Murray, H.L., Jenner, R.G., Gifford, D.K., Melton, D.A., Jaenisch, R., and Young, R.A. 2005. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122:947‐956
in the promoters of both mouse and human BIC genes. Putative NF-{kappa}B sites are present in the upstream region of the BIC promoter, and previous studies on the increased production of miR-155 in B cells have implicated NF-{kappa}B (15). This transcription factor
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