TAU OLIGOMERIC COMPLEX RMABMA5

Fluorescent Microscopy as a Tool to Elucidate Dysfunction and Mislocalization of Golgi Glycosyltransferases in COG Complex Depleted Mammalian Cells

for glycosylating host proteins, are mostly localized to the Golgi apparatus, and their localization is maintained in part by a protein vesicular tethering complex, the conserved oligomeric Golgi (COG) complex. Here we detail a combination of fluorescent lectin

三句话读懂一篇CNS：好奇心的发生机制，意念打字速度接近手机打字，古代粪便揭示肠道微生物信息...

物物种，这些工业化前、古老的基因组更像非工业化人群的肠道微生物组。 图 1：来源 Nature 2. Cell：外伤性脑损伤的病理新证据 外伤性脑损伤是导致人类伤残和死亡的原因之一。 2021 年 5 月 13 日，凯斯西储大学 Andrew A. Pieper 教授团队在 Cell 杂志上发表研究论文 Reducing acetylated tau is neuroprotective in brain injury。 该工作揭示了外伤性脑损伤诱导 tau 蛋白乙酰化的分子机制，对于临床治疗外伤

In Vivo Detection of Oxidized Proteins: A Practical Approach to Tissue-Derived Mitochondria

to oxidative modification of proteins, lipids, and DNA. AAA proteases of the inner mitochondrial membrane, paraplegin and AFG3L2, participate in the biogenesis and maintenance of respiratory chain complexes. These proteins form hetero-oligomeric paraplegin/AFG