相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 规格:
200 UG
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
receptor 1 (TRAIL-R1/DR4), TRAIL-R2 (KILLER/APO-2/DR5/TRICK), CD95 (Fas, APO-1), or TNF receptor 1 (TNF-R1), this complex is termed death-inducing signaling complex (DISC). The compositions of the various DISCs have been intensively studied in the last 12
by LMP1’s ability to bind molecules involved in the signaling cascade of the TNF-receptor family members ( 9 – 12 ). In analogy to known receptors such as CD40 or TNF-R2, LMP1 activates cellular transcription factors of the NFкB and AP
/Apol(23%同源)的同源序列。TRAIL/Ap02L属于Ⅱ型膜蛋白,但可以被水解后释放,存在于各种组织中。TRAIL有两个细胞膜受体:TRAIL-R1(DR4)和TRAIL-R2(DR5)。这两个受体都有细胞内的死亡结构域,可以传递凋亡信号。此外,还有两个缺陷受体(decoyreceptor):DcRl和DcR2,也被称之为TRAIL-R3和TRAIL-R4。 尽管Ap02/TRAIL的生物活性与诱导凋亡有关,但其确切的生理功能并不十分清楚。小鼠Ap02L/TRAIL基因敲除模型显示
技术资料暂无技术资料 索取技术资料








