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文献和实验The Chimeric Human/Mouse Model of Angiogenesis
vascular development are tightly regulated. However, when the molecular and biochemical mechanisms controlling angiogenesis are disrupted, uncontrolled neovascularization can contribute to a number of pathologies. In fact, several clinically important human
In Vivo Study of HCV in Mice with Chimeric Human Livers
has been significantly hampered by difficulties in establishing in vitro and in vivo models of viral replication. This chapter reviews development, validation, and early application of a mouse model with a chimeric human liver.
Detection of Class Switching and IgE Synthesis in Human B Cells
events leading to IgE synthesis. This chapter will illustrate how human B cells (na�ve or memory) can be purified, stored, and cultivated in medium that is permissive for IgE synthesis and stimulated with IL-4 or IL-13 and CD40 activation
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