- ￥5792
- 赛默飞（Thermo Fisher）
- MA547162
- 2025年07月10日
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文献和实验Monitoring Oncogenic B-RAF-Induced Senescence in Melanocytes
The B-RAF kinase is a downstream effector of the RAS family of proto-oncogenes and is constitutively activated in the majority of human melanomas. The common oncogenic B-RAFV600E mutant cooperates with additional genetic lesions to transform
Cell-Free Assay System for Ras- and Rap1-Dependent Activation of MAP-Kinase Cascade
the MEK activation (5 –7 ). Many MEK kinases have been identified: these include c-Raf-I (8 –10 ), B-Raf (11 –15 ), Mos (16 –17 ), and mStel 1 (11 –18 ). There are several lines of evidence that Ras is an upstream regulator of c-Raf
Two-hybrid analysis of genetic
has been used to examine interactions between small sets of tens of proteins (Finley and Brent,1994; Finley and Brent,1995; Reymond and Brent,1995),larger sets of hundreds of proteins (R.L.F.and R.B.,unpublished),to screen libraries (Bendixen et al.,1994
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