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文献和实验Translocation of p47phox and Activation of NADPH Oxidase in Mononuclear Cells
subunits. Equimolar amounts of p47phox and p67phox in the cytosol combine to a form a highly basic 250 kDa protein. During activation, this complex migrates from the cytosol to the membrane where this complex combines with cytochrome b558 , which in turn
Interferon-gamma IFN-γ)–induced remodeling of the bacterial phagosome for pathogen clearance elicits the aid of a new family of GTPases termed the p47 IRGs. Members of this group reside primarily on ER-Golgi membranes before translocating
Analysis of Protein Phosphorylation in Human Neutrophils
sites of a multisite-phosphorylated protein can be analyzed by using two-dimensional tryptic phosphopeptide mapping. This chapter describes a phosphorylation protocol and the analysis of the phosphorylation of a neutrophil protein, p47phox
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