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文献和实验HIV-1-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC)
-1-infected cells thereby decreasing viral load (1 –5 ) . The effector cells for ADCC are natural killer (NK) cells, that mediate lysis in a non-MHC restricted fashion. NK cells expressing CD16+ low affinity Fc-receptors bind to antibody which specifically
Methods for Measuring Antibody-Dependent Cell-Mediated Cytotoxicity In Vitro
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a relevant characteristic to measure for a number of therapeutic monoclonal antibodies (mAbs) under development. ADCC is a mechanism by which antibody-opsonized, infected, or cancerous
secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
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