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文献和实验Tracking Antigen-Experienced Effector T Cells In Vitro and In Vivo
The TCR complex is a multisubunit complex, comprising at least eight transmembrane units. The clonotypic TCR α and β chains are responsible for antigen recognition, whilst the invariant chains of the CD3 complex (δ, ɛ and γ) and two zeta (ζ
Age-Related Alterations to Natural Killer Cell Function
56. NK cells do not rearrange immunoglobulin (Ig) or T-cell receptor (TCR) genes. Therefore, neither Ig nor the TCR-CD3 complex is expressed at the cell surface, except for the zeta (ζ) chain. Both markers, CD16 and CD56, have been used to analyze age
Is physically and functionally coupled with T cell receptor-zeta-CD3 signal transducer complex CD5+ B cells produce “generalist antibodies” - polyreactive low affinity "natural" antibodies to exogenous antigens (tetanus toxoid, lipopolysaccharide
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