- ￥5056
- 赛默飞（Thermo Fisher）
- MA531480
- 2025年07月13日
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文献和实验Analysis of p21CDKN1A Recruitment to DNA Excision Repair Foci in the UV-Induced DNA Damage Response
The cyclin-dependent kinase (CDK) inhibitor p21CDKN1A (also known as p21waf1/cip1 ) is a well known player of the G1 and G2 phase cell cycle checkpoints, which are activated in response to DNA damage. In addition, p21 interacts directly
Quantification of Cell Cycle-Arresting Proteins
blockage is mainly mediated by the persistent upregulation of one or more cyclin-dependent kinase inhibitors (CKIs), including (though not limited to) p16 INK4A and p21 CIP1 and p27 KIP1 . CKIs operate by binding to cyclin-dependent kinases (CDKs
Measurement of Changes in Apoptosis and Cell Cycle Regulatory Kinase Cdk2
with degradation of its inhibitors p21Cip1 and p27Kip1 by activated caspases. Methods for measuring Cdk2 changes in activity in quiescent cells undergoing apoptosis are detailed in this chapter.
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