- ￥5130
- 赛默飞（Thermo Fisher）
- MA527731
- 2025年06月25日
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文献和实验Identifying Inhibitors of ATM and ATR Kinase Activities
The Ataxia Telangiectasia mutated (ATM) and the ATM and Rad3-related (ATR) proteins function in partially overlapping DNA damage checkpoint pathways that orchestrate the cellular response to DNA damage. Both proteins belong to a growing
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases
The Ataxia telangiectasia -mutated (ATM) and the ATM-Rad3-related (ATR) kinases are master regulators of the DNA damage-signaling pathways that respond to a wide variety of DNA damage. In this chapter, we describe an in vitro biochemical
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