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文献和实验by the alternative (left) and the classical pathway (right). Signaling through TNFR, IL-1R, or Toll-like receptors (TLR) activates the classical NF-κB pathway involving predominantly the β and γ subunits of the IKK complex. Nuclear translocation
type proteins to identify the role of the endogenous protein in regulating muscle fiber atrophy. The plasmids used encode a dominant negative form of the inhibitor of kappaB kinase beta (IKKβ) fused to green fluorescent protein (GFP), a constitutively
,你可以试试,只是稍微比较贵点, myskyld lwjssry wrote: 楼主为什么不做IKK dominant negtive的稳定筛选? 我用的是BAY 11-7082,是IKK抑制剂,效果不错,sigma的,可以试试 Merck 公司提供很多NF-kappa B Activation Inhibitors: 5HPP-33 Acetyl-11-keto-beta-Boswellic
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