FACTOR XII HEAVY CHAIN ANTIBOD

Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy

of cardiac hypertrophy. It was accompanied by enlargement of cardiac myocytes and induction of -myosin heavy chain (MHC) and MLC-2 gene expression. Multiple injections of 182-kDa protein-specific polyclonal antibody into the circulation of aorta-constricted

Delineation of Sequences Essential for Specific Promoter Activation During Pressure Overloaded Hypertrophy or Factor-Induced Hypertrophy

, and downregulated the expression of the -Myosin heavy chain (MHC) gene. To identify the cis-acting regulatory element(s), which controls induction of the -MHC gene in acute pressureoverloaded cardiac hypertrophy induced by the 182-kDa protein, the -MHC promoter

Use of chromatin immunoprecipitation (chip) to detect transcription factor binding to highly homologous promoters in chromatin isolated from unstimula

with the regulatory element of interest. In this report, we demonstrate the selective in vivo association of NF-κB, p300 and CREB with the human Iγ1 promoter located in the intronic region upstream of the Cγ1 exons in the immunoglobulin heavy chain locus