DNA/RNA OXIDATIVE DAMAGE MARKE

Oxidative Damage in Huntington’s Disease

for huntingtin, has been unambiguously identified. On the other hand, the mechanisms by which the mutation causes the disease are not completely understood yet. However, defects in the energy metabolism of affected cells may cause oxidative damage

Capillary Electrophoresis of Oxidative Dna Damage

Urinary 8-hydroxy-2′-deoxyguanosine (8OHdG) is an excellent marker of oxidative DNA damage. Until now, urinary 8OHdG has been measured by high-performance liquid chromatography with electrochemical detection. A simple and sensitive method

Simultaneous In Situ Detection of DNA Fragmentation and RNA/DNA Oxidative Damage Using TUNEL Assay and Immunohistochemical Labeling for 8-Hydroxy-2-De

and there is a great deal of research aimed at unraveling the molecular mechanisms underlying oxidative damage to DNA by so-called reactive oxygen species (ROS) and oxygen radicals. Oxidative damage has been implicated in a wide variety of neurodegenerative disorders