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文献和实验yirenzhe ERK1与ERK2到底有什么区别?除分子量不同外。 doctormy ERK1 和 ERK2 的区别是个很大的研究课题,还有很多未知啊,呵呵 目前研究认为,ERK1 和ERK2 的上游激活路径高度相似,而且他们目前已知的下游靶点也非常一致。但当前有关区别的研究主要还是侧重于具体的生物学功能方面:人们发现ERK2与人体发育密切相关,对于学习和记忆的功能非常重要,而ERK1则不然;有学者认为
Localization and Trafficking of Fluorescently Tagged ERK1 and ERK2
The action of ERK1 and ERK2 activity on the nuclear substrates requires crossing the nuclear envelope and the localization of phospho-ERK into the nucleus. The nucleo-cytoplasmic trafficking of ERK is therefore crucial for the correct
Lentiviral Vectors to Study the Differential Function of ERK1 and ERK2 MAP Kinases
Accumulating evidence indicates that p44ERK1 and p42ERK2 mitogen-activated protein kinases (MAPKs) have distinct quantitative roles in cell signaling. In our recently proposed model of regulation of ERK1 and ERK2, p42 plays a major role
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