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文献和实验The steroidogenic acute regulatory (StAR) protein, a novel mitochondrial protein, is involved in the regulation of steroid hormone biosynthesis through its mediation of the intramitochondrial transport of the steroid substrate, cholesterol
Analysis of Trophoblast Giant Cell Steroidogenesis in Primary Cultures
acute regulatory protein (StAR) and 3β-hydroxysteroid dehydrogenase/isomerase (3βHSD). To obtain giant cells, uterine implantation sites are sliced in half, and the trophoblast giant cell layers are separated from the surrounding decidua by scraping
Estrogen-Deficient Mouse Models in the Study of Brain Injury and Disease
into the mitochondrion of steroidogenic cells (1-3). This transfer of cholesterol into the mitochondrion is facilitated by the steroidogenic acute regulatory protein (StAR) (1). This is the rate-limiting step in androgen biosynthesis, as the cholesterol
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