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文献和实验Isolation and Culture of Squamous Cell Carcinoma Lines
Cutaneous squamous cell carcinoma (SCC) keratinocytes readily grow, expand in culture, and continuously passage, suggesting either spontaneous immortalisation at the early stage of culture or inherent proliferative capacity. One feature
Epigenome and DNA Methylation in Oral Squamous Cell Carcinoma
in epigenetic changes includes the posttranslational modifications of histones, mainly phosphorylation, deacetylation changes, and in the ubiquitinylation status. Oral squamous cell carcinoma is the most common malignancy of the oral cavity, and epigenetic
Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
isolated based on the presence of specific cell surface antigens. In head and neck squamous cell carcinomas, we have shown that the CSCs are contained within the CD44+ subset of tumor cells. This subset contains cells capable of initiating tumor growth
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