- ￥6972
- 赛默飞（Thermo Fisher）
- 2956-RBM17-P1
- 2025年07月12日
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文献和实验Eukaryotic DNA Mismatch Repair In Vitro
Mismatch repair corrects biosynthetic errors generated during DNA replication. Mismatch repair deficiency causes a mutator phenotype and directly underlies hereditary nonpolyposis colorectal cancer and some sporadic cancers
DNA mismatch repair plays an important role in mutation avoidance by recognizing and correcting mismatched bases and loops prior to their fixation as mutations. When mismatch repair is defective, cells exhibit elevated rates of spontaneous
In Vitro DNA Mismatch Repair in Human Cells
The in vitro DNA mismatch repair (MMR) assay is a very useful technique for studying the functions and the mechanisms of the MMR system in genome maintenance. This assay has been effectively used to evaluate MMR proficiency in various tumor
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