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文献和实验encephalomyelitis (EAE)—a model of multiple sclerosis (MS), collagen II (CII)-induced arthritis (CIA)—a model of rheumatoid arthritis (RA). Pathogenic T cells in EAE utilize a restricted repertoire of genes encoding the T-cell receptor (TCR) (1 ). For example
Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
Figure 13.6.3 Glucocorticoid receptor [F602S] LBD binding to the coactivator peptide PGC‐1 alpha (130‐154) (biotin‐DGTPPPQEAEEPSLLKKLLLAPANT‐CONH2) (A ) or the corepressor peptide NCoR (2251‐2275) (biotin
【进展|热点】BLOOD: 雌激素受体通过上调IRF4促进DC的分化
-stimulating factor (GM-CSF) directs the development of new dendritic cells (DCs). This pathway is influenced by environmental factors, and we previously showed that physiologic levels of estradiol, acting through estrogen receptor alpha (ER), promote the GM
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