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NBS1 Peptide

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  • ¥600 - 1600
  • Abbiotec已认证
  • 美国
  • 350525
  • 2025年07月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

    • 保质期

      参照说明书可保存1-2年

    • 英文名

      NBS1 Peptide

    • 库存

      一定量库存

    • 供应商

      华拓生物

    • 规格

      0.1 mg

    产品细节图片1
    产品名称: NBS1 Peptide
    产品链接: http://www.abbiotec.com/peptides/nbs1-peptide
    货号: 350525
    规格: 0.1 mg
    产品描述: Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11/RAD50/NBN (MRN) complex, which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. NBS1 modulates the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. Defects in NBS1 are the cause of Nijmegen breakage syndrome, cancer predisposition, and anemia.
    序列: The synthetic peptide used to raise the antibody Cat. No. 200163 is selected from a sequence within the C-term region of human NBS1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
    分子式: C99H150N26O31S1
    分子量: 2232.5 g/mol
    纯度: Purity > 80% by HPLC
    别名: Nibrin; Nijmegen breakage syndrome protein 1; Cell cycle regulatory protein p95; NBN; NBS; NBS1; P95
    形态: Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
    溶解方法: Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
    保存方法: Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

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    图标文献和实验
    相关实验
    • peptide

         二个以上的α -氨基酸以肽键连接起来而形成的化合物。根据构成氨基酸的数目 2、 3、 4……叫做二肽( dipeptide)、三肽、四肽……。大体上由 10以下的肽键形成的肽总称为寡肽   ( Oligopeptide),由多数肽键构成的肽总称为多肽。每个肽按照构成它的氨基酸的名称,从具有游离α -氨基的末端氨基酸依次命名。例如   称为甘氨酰丙氨酸的二肽。蛋白质是由一条或几条长链状多肽构成的。象谷胱甘肽和肌肽那样的低

    • Two dimensional peptide mapping

        This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol

    • Peptide Bioinformatics- Peptide Classification Using Peptide Machines

      Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research subjects, such as functional site prediction, protein structure identification, and protein function recognition

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