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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
CaMKII Substrate Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | CaMKII Substrate Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/CaMKII-Substrate-Peptide |
| 货号: | 350007 |
| 规格: | 1 mg |
| 产品描述: | This peptide is a substrate (Km = 7.5 mM) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent. |
| 序列: | Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ser-Ser-NH2 or PLSRTLSVSS-NH2 |
| 分子式: | C44H80N18O15 |
| 分子量: | 1045.1 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Substrate: Glycogen synthase; GYS1; GYS; Enzyme: Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968 |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Study of Substrate Specificity of MAPKs Using Oriented Peptide Libraries
, particularly mass spectroscopy, has greatly facilitated this analysis (1 –3 ), although usually the investigator must still perform large scale biochemical purification of the presumed substrate to determine its identity. The use of oriented peptide library
Peptide substrate identification for yeast Hsp40 Ydj1 by screening the phage display library
We have identified a peptide substrate for molecular chaperone Hsp40 Ydj1 by utilizing the combination of phage display library screening and isothemol titration calirimetry (ITC). The initial peptide substrate screening for Hsp40 Ydj
In Vitro Peptidoglycan Synthesis Assay with Lipid II Substrate
Bacterial cell wall peptidoglycan is synthesized from lipid II precursor by two reactions. Glycosyltransferases polymerize the glycan chains and transpeptidases form the peptide cross-links. The bifunctional class A penicillin-binding
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