- ￥4218
- BioLegend
- 331918
- 美国
- 2025年07月14日
- 免疫荧光，流式
- 小鼠
- 人
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
APC anti-human CD335 (NKp46)
- 抗体英文名：
APC anti-human CD335 (NKp46)
- 应用范围：
免疫荧光，流式
- 宿主：
小鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
小鼠
- 保质期：
2-3年左右
- 适应物种：
人
- 标记物：
APC
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 tests
APC anti-human CD335 (NKp46) Antibody
9E2
Catalog# / Size 331917 / 25 tests
331918 / 100 tests
Clone
Regulatory Status RUO
Other Names NKp46, NCR1
Isotype Mouse IgG1, κ
Description CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family
which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and
lysis, and is exclusively expressed on CD3 CD56 NK cells, suggesting it is a universal marker for
NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor
(NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class Iunprotected cells.
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Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen NKp46-Fc fusion protein
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography and conjugated with APC under optimal
conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged
exposure to light. Do not freeze.
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CD46 分子 CD46 常用单克隆抗体或代号： HULYM5,J48 主要表达细胞： 广泛,Leu,Pt [NL] 分子质量(kDa)和结构： gp56- 66,膜辅助因子蛋白(MCP) 功 能： 调节补体活化,裂解C3b ,C4b膜辅助因子蛋白 CD46 Aka membrane cofactor protein (MCP) Cofactor for Factor
网络 四、膜辅蛋白（CD46） 膜辅蛋白（membrane cofactor protein,MCP）由Cole等（1985）应用C3b亲和层析在外周血淋巴细胞上发现的一种膜蛋白。由于其奇特的电泳特征，起初被命名为gp45-70，但进一步研究发现，它对I因子介导的对C3b和C4b的裂解有辅助活性，故更命为MCP。鉴于MCP
Detection of Cell Membrane-Bound CD46 Using Flow Cytometry
on several distinct human cell types have demonstrated that CD46 also plays decisive roles in immuneregulation. The growing recognition of CD46 as key regulator in several vital biological processes, led to increased demand in sensitive methods for monitoring CD46
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