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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
冷冻-20℃
- 英文名:
7α,27-dihydroxy-4-cholesten-3-one
- 库存:
999+
- 供应商:
上海维亦特生物科技有限公司
- CAS号:
192187-67-0
别名:7α,27-dihydroxy-4-cholesten-3-one
光敏性:Yes
分子式:C27H44O3
分子量:416.636
稳定性:1 Year
存储:冷冻-20°C
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文献和实验. This method is based on the conversion of the primary cytochrome P450 metabolite, 7α-hydroxycholesterol, into 7α-hydroxy-4-cholesten-3-one in a reaction catalyzed by exogenous cholesterol oxidase, followed by chromatographic separation with monitoring at 254
for the determination of cholesterol 7α-hydroxylase acttvity based on the conversion by cholesterol oxidase of the primary P450 metabohte 7α-hydroxycholesterol to 7α-hydroxy-4-cholesten-3-one, which can be detected at 254 nm.
The dipeptidic dihydroxyethylene isostere (27, 3R , 4R , 5S )-5-tert -butyloxy-carbonylamino-3,4-dihydroxy-2-isopropyl-3,4-O,O -isoprop-ylidene-6-cyclohexyl-hexanoic acid, 15 , is a representative building block of an important class
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