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- 技术资料
- 亚型:
IgG2a, kappa
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
12 months
- 级别:
一抗
- 供应商:
武汉益普生物科技有限公司
- 宿主:
Mouse
- 应用范围:
ELISA, FCM, Neutralization
- 浓度:
1 mg/ml
- 抗体英文名:
InVivoMAb Anti-Human ACE2 Antibody (3E8#)
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥2588.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥9188.0 |

| Product name | InVivoMAb Anti-Human ACE2 Antibody (3E8#) |
| Catalog No. | HV157020 |
| Target | Angiotensin-converting enzyme homolog, ACE2, ACEH, Metalloprotease MPROT15, Angiotensin-converting enzyme-related carboxypeptidase, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase |
| Clonality | Monoclonal |
| Host species | Mouse |
| Species reactivity | Human |
| Applications | ELISA, FCM, Neutralization |
| Isotype | IgG2a, kappa |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Concentration | 1 mg/ml |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact with the lab for this information. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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文献和实验中科院高福院士课题组 2020 年发表了哪些重要的研究成果?
性。 图源:Cell Discovery 8、筛选出新冠病毒中和抗体DOI: 10.1126/science.abc22412020 年 5 月 13,高福院士联合高峰在 Science 发文:A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2。该研究报告了从一个康复中的患者中分离出四种人源单克隆抗体,所有这些抗体均显示中和能力。抗体 B38
). Partial deletion of the cytoplasmic domain of SARS-CoV S protein (SARS-CoV-St19) allowed efficient incorporation into the VSV particle that enabled the generation of a high titer of pseudotype virus. Neutralization assay with anti-SARS-CoV antibody
免疫分析中出现问题的一个常见原因是干扰性抗体,如众所周知的人抗鼠抗体(Human anti-mouse Antibodies,HAMA)、一般的抗动物抗体、嗜异性抗体(Id)或类风湿因子(rheumatoid factors,RF)。有趣的是,由于今天的治疗性单克隆抗体药物几乎完全是人源化的,所以真正的HAMA的流行率正在稳步下降。然而,随着近年来类风湿和过敏性疾病等发病率的上升,抗体引起的干扰在未来仍将具有高度的临床相关性,并且似乎进一步增加患病率。一般来说,这些抗体干扰主要发生在夹心
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