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- BioLegend
- 142909
- 美国
- 2025年07月15日
- 免疫荧光，流式
- 大鼠
- 小鼠
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- 技术资料
- 抗体名：
PE/Cyanine7 anti-mouse GARP (LRRC32)
- 抗体英文名：
PE/Cyanine7 anti-mouse GARP (LRRC32)
- 浓度：
0.2 mg/ml
- 应用范围：
免疫荧光，流式
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
大鼠
- 保质期：
2-3年左右
- 适应物种：
小鼠
- 标记物：
PE/Cyanine7
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
25ug
PE/Cyanine7 anti-mouse GARP (LRRC32) Antibody
F011-5
Catalog# / Size 142909 / 25 µg
142910 / 100 µg
Clone
Regulatory Status RUO
Other Names LRRC32, Garpin, Glycoprotein A repetitions predominant
Isotype Rat IgG2a, κ
Description Glycoprotein A Repetitions Predominant (GARP), also known as leucine rich repeat containing
protein 32 (LRC32), is a 80 kD type I membrane glycoprotein with 20 leucine rich repeats in
the extracellular portion of the protein. GARP was found on the surface of megakaryocytes,
platelets, and activated Tregs. It serves as a receptor for latent TGF-β. Recent evidence
suggests that GARP may play a role in controlling suppressor function of Tregs. A mutation in
GARP has been reported in a large Samaritan kindred with Usher syndrome type 1. In
addition, it has been found that GARP mRNA is highly amplified in different tumors, which
indicates that tumor cells may use GARP to express TGF-β or to capture TGF-β from their
surroundings, resulting in local suppression of anti-tumor immune responses or the induction
of Tregs.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Mouse GARP (extracellular domain)
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under
optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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Characterization of Whole Body Cholesterol Fluxes in the Mouse
in this pathway. This article describes in detail a variety of experimental approaches to measure cholesterol fluxes in the hepatobiliary system as well as in the intestinal pathway. Curr. Protoc. Mouse Biol. 1:413?427 © 2011 by John Wiley & Sons
Immunofluorescent Staining of Mouse and Rat Leukocytes
-up, please see description in "Procedure for Setting Compensation for Multi-Color Flow Cytometric Analysis". For reducing FcgII/IIIR-mediated antibody binding (or binding of SAv-PE or SAv-Cy-Chrome) which could contribute to background, the use of anti-mouse CD32/CD
Phycoerythrin conjugation protocol
and Centricon concentrators. Add 0.5% sodium azide. Store at 4 °C protected from light. Do not freeze. Figure 1. Analysis of column eluate fractions from PE conjugation of monoclonal antibody IB4 (murine IgG2a, anti-human CD
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