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- 124624
- 2025年07月15日
- 大鼠
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- 技术资料
- 抗体名：
PerCP/Cyanine5.5 anti-mouse CD40
- 抗体英文名：
PerCP/Cyanine5.5 anti-mouse CD40
- 浓度：
0.2 mg/ml
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
大鼠
- 保质期：
2-3年左右
- 适应物种：
小鼠
- 标记物：
PerCP/Cyanine5.5
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 μg
PerCP/Cyanine5.5 anti-mouse CD40 Antibody
3/23
Catalog# / Size 124623 / 25 µg
124624 / 100 µg
Clone
Regulatory Status RUO
Other Names Bp50, TNFRSF5
Isotype Rat IgG2a, κ
Description CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of
the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal
epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34
hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype
switching and, in combination with other signals such as IL-4, protects B cells from surface Iginduced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154
(gp39), which is expressed on activated T cells, is important in costimulation and immune
regulation.
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Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Recombinant mouse CD40 protein
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5
under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
molecules CD40, CD80, and CD86 (5 ,6 ), and production of cytokines such as interleukin-12 (IL-12) (7 -9 ), IL-6 (10 ), and interferon α (IFN-α) (10 ,11 ). Moreover, DC can process antigens in various forms by different pathways and induce high levels
【进展|热点】Science:胰腺腺癌治疗新思路-CD40分子激活抗肿瘤细胞
the combination of an agonist CD40 antibody with gemcitabine chemotherapy in a small cohort of patients with surgically incurable PDA and observed tumor regressions in some patients. We reproduced this treatment effect in a genetically engineered mouse model
Fluorochrome Absorption and Emission Spectra
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
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