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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Biotin anti-mouse CD105
- 抗体英文名:
Biotin anti-mouse CD105
- 浓度:
0.5 mg/mL
- 应用范围:
免疫荧光,流式
- 宿主:
大鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
大鼠
- 保质期:
2-3年左右
- 适应物种:
小鼠
- 标记物:
Biotin
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
500 μg
Biotin anti-mouse CD105 Antibody
MJ7/18
Catalog# / Size 120403 / 50 µg
120404 / 500 µg
Clone
Regulatory Status RUO
Other Names Endoglin
Isotype Rat IgG2a, κ
Description CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as
endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and
upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and
some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β
signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth
factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for
identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor
imaging and prognosis, and has therapeutic potential for some solid tumors and other
angiogenic diseases.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Inflamed mouse skin
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with biotin under optimal
conditions.
Concentration 0.5 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze
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A number of endogenously biotinylated proteins are found in both cytosol and mitochondria of mammalian cells from many tissues, including liver, spleen, pancreas, kidney, and intestine. Therefore, caution should be taken when using the biotin
in the nucleus in human cell cultures we designed several RNA-biotin based pulldown assays which can be used alone or in combination with other known assays such as ChIP and Flag-tagged pulldown assays. Three protocols are explained
CGH of Biotin Labeled DNA vs Digoxigenin Labeled DNA
DAY 1: 1) Reprecipitate DNA's Add the following DNA's to a 1.5 ml centrifuge tube, mixing with pipet: 20 ug Cot-1 DNA (~20ul) ~200 ng Biotin labeled DNA (~10ul) ~200 ng Digoxigenin labeled DNA (~10ul) Add 1/10th
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