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- 2025年12月11日
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- 详细信息
- 技术资料
- 抗体名：
Verenafusp alfa
- 抗体英文名：
Anti-Human INSR/CD220 antibody
- 靶点：
INSR/CD220，INSR, IR, CD220, Insulin receptor
- 适应物种：
human
- 保质期：
12 months
- 目录编号：
CAS：2699034-69-8
- 级别：
Research Grade
- 供应商：
苏州艾洛蒙
- 克隆性：
Monoclonal
- 保存条件：
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
- 形态：
Liquid
- 亚型：
F(ab')2 - G1 - kappa
- 规格：
1mg
Verenafusp alfa 是一种靶向 INSR 的嵌合抗体。Verenafusp alfa is an INSR-targeting chimeric antibody
Insulin is a classic example of a naturally occurring protein produced by recombinant technology. Human insulin was the first recombinant protein commercially produced for therapeutic use. Before the availability of recombinant insulin, diabetic patients relied on insulin purified from the pancreases of pigs and cows, which occasionally resulted in serious immune reactions. Recombinant human insulin has dramatically improved the therapy for diabetes. Human insulin is expressed as a precursor form, single-chain prepro-insulin, which contains extra amino acids that are subsequently cleaved by proteases during the normal processing of this protein hormone. The mature insulin molecule consists of two short polypeptide chains A and B that are linked by two disulfide bonds. Recombinant human insulin was originally produced as the form of proinsulin that subsequently underwent enzymatic cleavage to form the active insulin molecule, but currently it is produced by expressing A and B chains separately, then refolding them into a mature insulin molecule.
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