
Anti-Human KIT antibody (Briqu
ilimab Biosimilar )收藏
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- 详细信息
- 技术资料
- 抗体名:
Briquilimab
- 靶点:
KIT, SCFR, PBT, CD117, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit
- 适应物种:
human
- 保质期:
12 months
- 级别:
Research Grade
- 供应商:
苏州艾洛蒙
- 克隆性:
Monoclonal
- 保存条件:
Store at -20°C for 12 months (Avoid repeated freezing and thawing)
- 形态:
Liquid
- 亚型:
Human IgG1, κ
- 规格:
1mg
Briquilimab (JSP-191) 是针对 CD117 (c-Kit) 的无毒人源化单克隆抗体,用于消耗造血干细胞 (HSC)。它被应用于重度联合免疫缺陷 (SCID) 治疗中,以清空宿主骨髓生态位,为供体造血干细胞移植及免疫重建创造条件。Briquilimab (JSP-191), a non-toxic humanized monoclonal antibody, targets CD117 (c-Kit) to deplete hematopoietic stem cells (HSCs), providing a safe approach for clearing host marrow niche to facilitate adequate donor HSC engraftment and immune reconstitution, primarily in the treatment of severe combined immunodeficiency (SCID)
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Anti-Human KIT antibody (Briquilimab Biosimilar )
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