APC anti-human CD206 (MMR)

APC anti-human CD206 (MMR) Antibody
15-2
Catalog# / Size 321109 / 25 tests
321110 / 100 tests
Clone
Regulatory Status RUO
Other Names MMR (macrophage mannose receptor), MR (mannose receptor), CD206, MRC1
Isotype Mouse IgG1, κ
Description Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known
as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that
belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and
hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of
microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates
endocytosis and phagocytosis, induces activation of macrophages and antigen presentation,
plays an important role in host defense, and provides a link between innate and adaptive
immunity.
Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen Purified human mannose receptor
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography, and conjugated with APC under optimal
conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.