- ￥1825
- ACROBiosystems
- FABm003-05
- CN
- 2025年12月02日
- Flow Cytometry (Evaluation of the expression of CD8 on Human cells).
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- 详细信息
- 技术资料
- 靶点：
CD8
- 应用范围：
Flow Cytometry (Evaluation of the expression of CD8 on Human cells).
- 抗原来源：
Mouse
- 库存：
1
- 供应商：
ACROBiosystems
- 保存条件：
● Store at 2-8 °C for 12 months. Please protect from light and avoid repeated freeze-thaw cycles.
- 形态：
液体
- 亚型：
Mouse IgG1
- 规格：
50tests
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
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