Biotinylated SIRP-α Fc Chimera

te through the N-terminal domain allowing it to bind to multivalent saccharide ligands. Gal-3 is expressed in the nucleus, cytoplasm, mitochondrion, cell surface and extracellular space. Gal-3 plays a role in numerous cellular functions including apoptosis, innate immunity, cevariants. Gal-3 plays an important role in the pathogenesis of neuroinflammatory and neurodegenerative disorders, such as multiple sclerosis, Alzheimer's disease, Parkinson's disease, and Huntington's disease. On the other hand, tHPS-1，是一种跨膜蛋白，SIRP-α在髓系细胞膜上高表达，如巨噬细胞、粒细胞、单核细胞和髓样树突状细胞。它可以调节细胞迁移和吞噬活动，以及免疫稳态和神经网络的形成。