NKG2D/CD314 His Tag Protein, H

NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. NKG2D also plays an important role in viral control. NKG2D is a major recognition receptor for the detection and elimination of transformed and infected cells as its ligands are induced during cellular stress, either as a result of infection or genomic stress such as in cancer. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.