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- 详细信息
- 技术资料
- 供应商:
优爱
- 规格:
100μg/500μg
| 规格: | 100μg | 产品价格: | ¥2400.0 |
|---|---|---|---|
| 规格: | 500μg | 产品价格: | ¥9600.0 |
ACVR2A (activin A receptor type 2A) belongs to a receptor family that mediates the functions of activins, members of the transforming growth factor-beta (TGF-β) family of ligands with multiple biological functions. The TGF-β signaling pathway is involved in the regulation of cell proliferation, differentiation, migration, and apoptosis of colon cancer. The mutation rate of ACVR2A is approximately 60%, making it the most frequently mutated gene in hypermutated colon cancer. However, the expression profiles of ACVR2A and its biological function in colon cancer tumorigenesis and progression are largely unknown.
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