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<p> 2 to 8 °C for 2 weeks under sterile conditions;</p><p> -20 °C for 3 months under sterile conditions; </p><p> -80 °C for 24 months under sterile conditions.</p><p> Please avoid repeated freeze-thaw cycles. <br /></p>
- 供应商:
斯达特
- 规格:
1mg/5mg/25mg/50mg/100mg
| 规格: | 1mg | 产品价格: | ¥700.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥2700.0 |
| 规格: | 25mg | 产品价格: | ¥9000.0 |
| 规格: | 50mg | 产品价格: | ¥13000.0 |
| 规格: | 100mg | 产品价格: | ¥19000.0 |
CTLA-4 (Cytotoxic T-Lymphocyte-Associated Protein 4), also known as CD152, is a transmembrane protein expressed on the surface of activated T cells. It plays a role in the negative regulation of the immune response and is one of the key targets in immune checkpoint therapy. CTLA-4 shares the same ligands, B7 molecules (including CD80 and CD86), with CD28; however, unlike CD28, the binding of CTLA-4 to B7 molecules inhibits T cell activation. This inhibitory effect helps prevent excessive immune responses, but in the tumor microenvironment, tumor cells may exploit CTLA-4 to evade immune surveillance and attack.
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