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- 详细信息
- 技术资料
- 保存条件:
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
- 供应商:
斯达特
- 规格:
25T/100T
| 规格: | 25T | 产品价格: | ¥1000.0 |
|---|---|---|---|
| 规格: | 100T | 产品价格: | ¥2500.0 |
CD185, also known as CXCR5 or Burkitt lymphoma receptor 1 (BLR1), is a G protein-coupled receptor with seven transmembrane regions. It belongs to the CXC chemokine receptor family and specifically binds to the chemokine CXCL13. This protein is crucial for the migration of B cells into B cell follicles in the spleen and Peyer's patches, and it is also essential for the function of follicular helper T cells. CD185 is expressed in mature B cells, follicular helper T cells, and certain types of lymphoma, including Burkitt's lymphoma. Additionally, it may play a role in maintaining cardiac structure under pressure overload and in the formation of ectopic mucosa-associated lymphoid tissue during chronic inflammation.
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