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Folate receptor 4 (FR4), also known as folate receptor delta or IZUMO1R, is a protein encoded by the FOLR4 gene in humans. It is a subtype of the receptor for the vitamin folic acid and is primarily expressed on CD4 T lymphocytes, with lower expression on CD8 T cells. FR4 is highly expressed in regulatory T cells (Tregs) and is also found in tumor-associated macrophages (TAMs) and T follicular helper cells (TFH cells). This protein plays a role in immune regulation, as its high expression can distinguish Tregs from other T cells. Additionally, FR4 is involved in the high-affinity binding and transport of folate and folate analogs across the cell membrane.
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文献和实验. 2. Combining AbC™ anti-Rat/Hamster and ArC™ Amine Reactive Compensation Bead Kits The ArC™ Amine Reactive Compensation Bead Kit (Cat. no. A10346) is designed to facilitate compensation when using any of the LIVE/DEAD® fixable dead cell stains
的优点就是对光稳定性，Cy5 和 AlexaFluor 647 以花青素为基础，因此有着和花青素一样的特点即耐光性较差。极好的亮度和耐光性使CF ? 640R被理想的用于共聚焦显微镜和单分子成像等条件苛刻的检测中。CF 647、AlexaFluor 647, ATTO 647N, DyLight649等远红外荧光染料；以花青素为基础的远红外荧光染料CF647 比Cy 5、Alexa Fluor 647 明亮。CF 660、AlexaFluor® 660, Allophycocyanin (APC
secondary antibody review -- data from 99 publications
Signaling 18 IgG Alexa Fluor 488 immunocytochemistry 1:2000 18 IgG Alexa Fluor 568 immunocytochemistry 1:2000 19 donkey IgG HRP western blot 1:3000 detect antibody binding in mouse epithelial cells Amersham Biosciences 19 goat
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