- ￥600 - 2100
- 斯达特
- 浙江杭州
- S0B1495
- 2025年10月09日
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- 详细信息
- 技术资料
- 保存条件：
<p>12 months from date of receipt / reconstitution, -20 °C as supplied</p>
- 供应商：
斯达特
- 规格：
25μl/100μl
| 规格： | 25μl | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2100.0 |
CCL17, also known as Thymus and Activation-Regulated Chemokine (TARC), is a protein that belongs to the C-C chemokine family. It is primarily produced by dendritic cells, endothelial cells, keratinocytes, and fibroblasts, and is highly expressed in the thymus. CCL17 plays a crucial role in immune regulation by recruiting lymphocytes and modulating immune function. It acts as a ligand for the C-C chemokine receptor type 4 (CCR4), which is highly expressed on helper T cells. This chemokine is involved in various biological processes, including T-cell development, trafficking, and activation of mature T cells. Additionally, CCL17 has been implicated in several diseases, such as chronic kidney disease, where it may promote renal fibrosis by inducing epithelial-mesenchymal transition. In the context of cancer, CCL17 can influence the tumor microenvironment by recruiting regulatory T cells and affecting tumor progression.
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