- ￥1257 - 2967
- 斯达特
- 浙江杭州
- S0B5275
- 2025年10月08日
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- 技术资料
- 保存条件：
12 months from date of receipt / reconstitution, 2 to 8 °C as supplied
- 供应商：
斯达特
- 规格：
25T/100T
| 规格： | 25T | 产品价格： | ￥1257.0 |
|---|---|---|---|
| 规格： | 100T | 产品价格： | ￥2967.0 |
CD184, also known as CXCR4 or fusin, is a 45 kD seven-transmembrane G-protein-linked CXC chemokine receptor. It is widely expressed on various human cells, including leukocytes, hematopoietic stem cells, epithelial cells, endothelial cells, and cancer cells. This receptor is specific for stromal-derived factor-1 (SDF-1, also called CXCL12) and plays a crucial role in cell migration, hematopoiesis, cell homing, and the proliferation of non-hematopoietic cells. Additionally, CXCR4 serves as a co-receptor for T-cell tropic HIV viruses, enabling their entry into human lymphocytes. In cancer, CXCR4 is involved in tumor cell survival, proliferation, migration, and metastasis, making it a potential therapeutic target.
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