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- 详细信息
- 技术资料
- 保存条件:
<p>12 months from date of receipt / reconstitution, 2 to 8 °C as supplied</p>
- 供应商:
斯达特
- 规格:
25μl/100μl
| 规格: | 25μl | 产品价格: | ¥1056.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥3700.0 |
CD45 is a type I transmembrane protein that is present in various isoforms on all differentiated hematopoietic cells (except erythrocytes and plasma cells). CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes via its extracellular domain (a form of co-stimulation), or by activating various Src family kinases required for the antigen receptor signaling via its cytoplasmic domain. CD45 also suppresses JAK kinases, and so functions as a negative regulator of cytokine receptor signaling.
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