- ￥600 - 2100
- 斯达特
- 浙江杭州
- S0B0528
- 2025年08月09日
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- 详细信息
- 技术资料
- 保存条件：
<p>12 months from date of receipt / reconstitution, -20 °C as supplied</p>
- 供应商：
斯达特
- 规格：
25μl/100μl
| 规格： | 25μl | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2100.0 |
RAC (Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
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