- ￥600 - 2100
- 斯达特
- 浙江杭州
- S0B0081
- 2025年07月18日
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- 详细信息
- 技术资料
- 保存条件：
12 months from date of receipt / reconstitution, -20 °C as supplied
- 供应商：
斯达特
- 规格：
25μl/100 μl
| 规格： | 25μl | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 100 μl | 产品价格： | ￥2100.0 |
The transmembrane protein, CD47, is recognized as an important innate immune checkpoint, and CD47-targeted drugs have been in development with the aim of inhibiting the interaction between CD47 and the regulatory glycoprotein SIRPα, for antitumor immunotherapy. Further, CD47 mediates other essential functions such as cell proliferation, caspase-independent cell death (CICD), angiogenesis and other integrin-activation-dependent cell phenotypic responses when bound to thrombospondin-1 (TSP-1) or other ligands. Mounting strategies that target CD47 have been developed in pre-clinical and clinical trials, including antibodies, small molecules, siRNAs, and peptides, and some of them have shown great promise in cancer treatment [PMID: 35931392].
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