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huayun / MIP-1γ/ CCL9, Mouse,

Recombinant,HYPC5231
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  • ¥4140
  • 华韵生物(Huayunbio)
  • HYPC5231
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名C-C Motif Chemokine 9; CCF18; Macrophage inflammatory Protein 1-gamma; Macrophage inflammatory Protein-related Protein 2; Small-inducible Cytokine A9; Scya10; Scya9 and CCL9.
    物种Mouse
    表达宿主E.coli
    序列信息Gln22-Gln122
    检索号P51670
    分子量11.6 kDa
    表观分子量15 kDa

    产品特性

    纯度 >90% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl,300mM NaCl,pH8.0.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    C-C Motif Chemokine 9 (CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of Chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and Chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity Receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its Receptor CCR1 (the most abundant Chemokine Receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.

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    图标文献和实验
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