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huayun / BDNF, Human, Recombin

ant,HYPC5096
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  • ¥5340
  • 华韵生物(Huayunbio)
  • HYPC5096
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名Brain-Derived Neurotrophic Factor; BDNF; Abrineurin
    物种Human
    表达宿主E.coli
    序列信息His129-Arg247
    检索号P23560
    分子量13 kDa
    表观分子量14 kDa
    生物活性 Immobilized Human TrkB-His at 2ug/ml (100 μl/well) can bind Human BDNF: Biotinylated by NHS-biotin prior to testing.The ED50 of Human BDNF is 47.58 ng/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase Receptor. It also binds with the LNGFR (for low-affinity Nerve Growth Factor Receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

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    图标文献和实验
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