huayun / GDNF/ ATF, Human, Recombinant,HYPC5095

huayun / GDNF/ ATF, Human, Rec

ombinant,HYPC5095
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  • ¥5340
  • 华韵生物(Huayunbio)
  • HYPC5095
  • 2025年07月12日
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    • 详细信息
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名Glial Cell Line-Derived Neurotrophic Factor; hGDNF; Astrocyte-Derived Trophic Factor; ATF; GDNF
    物种Human
    表达宿主E.coli
    序列信息Ser78-Ile211
    检索号P39905
    分子量15.1 kDa
    表观分子量17 kDa

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glyco Protein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric Protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.

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