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huayun / FGF-1/ FGFa/ FGF-acid

ic (Phe16-Asp155), Human, Recombinant,HYPC5025
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  • ¥2340
  • 华韵生物(Huayunbio)
  • HYPC5025
  • 2025年07月11日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Endothelial Cell Growth Factor; ECGFHeparin-Binding Growth Factor 1; HBGF-1; FGF1; FGFA
    物种Human
    表达宿主E.coli
    序列信息Phe16-Asp155
    检索号P05230
    分子量16 kDa
    表观分子量16 kDa
    生物活性 Measured in a cell proliferation assay using BALB/c 3T3 cells.The ED50 for this effect is 0.2-2 ng/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素<1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 50mM MOPS, 100mM Na2SO4, 1mM EDTA, pH 7.9.
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    FGF acidic, also known as ECGF, FGF-1and HBGF-1, is a non-glycosylated heparin binding Growth Factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. It is a mitogenic peptide that is produced by multiple cell types and stimulates the proliferation of cells of mesodermal, ectodermal, and endodermal origin. Its association with heparan sulfate is a prerequisite for activation of FGF Receptors. Internalized FGF acidic migrates to the nucleus where it is phosphorylated by nuclear PKC delta, exported to the cytosol, dephosphorylated, and degraded. Intracellular FGF acidic inhibits p53 activity and proapoptotic signaling.

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    图标文献和实验
    相关实验
    • miRNA技术详述

      (9): 1245–53. doi:10.1101/gr.6406307. PMID 17690206. ^ Bertone P, Stolc V, Royce TE, Rozowsky JS, Urban AE, Zhu X, Rinn JL, Tongprasit W, Samanta M, Weissman S, Gerstein M, Snyder M (December 2004). "Global identification of human transcribed sequences

    • [资源] 所有的看家基因(housekeeping genes)列表+引物设计服务

      ), mRNA 874 NM_006010 Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA 617 NM_005088 Homo sapiens DNA segment on chromosome X and Y (unique) 155 expressed sequence (DXYS155E), mRNA 524 NM_014754 Homo sapiens

    • 所有的看家基因(housekeeping genes)的列表+引物设计服务

              Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA    617 NM_005088                Homo sapiens DNA segment on chromosome X and Y (unique) 155 expressed sequence               (DXYS155E), mRNA                524 NM

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