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细胞名称:MO-91 Acute Myeloid Leukemia w Minimal Differentiation Human Cell Line
货号:SCC618
规格:vial of ≥1 x 10^6 vial
应用:Cells are tested negative for infectious diseases by a Human Essential CLEAR Panel by Charles River Animal Diagnostic Services.
Cells are verified to be of human origin and negative for inter-species contamination from mouse, rat, Chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination Clear panel by Charles River Animal Diagnostic Services
Cells are negative for mycoplasma contamination.
特点和优势:Phosphoproteomic analysis has identified the MO-91 human acute myeloid leukemia cell line as a suitable cellular model for the study of TEL-TRKC fusion-associated leukemia, as well as a model of M0 (minimally differentiated) acute myeloid leukemia, or AML.
储存及稳定性:SCC618 cells should be stored in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting functionality.
其他说明:This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
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文献和实验三句话读懂一篇 CNS:线粒体突变降低癌症死亡风险 57% 以上;解密大猩猩捶胸口之谜...
基因即为转座子,俗称垃圾 DNA。 2021 年 4 月 8 日,美国西南医学中心徐剑课题组在 Nature Genetics 在线发表论文 Silencing of LINE-1 Retrotransposons is a Selective Dependency of Myeloid Leukemia,该研究发现 逆转录转座子 LINE-1 不仅具有完整转座活性,而且在髓系白血病发生中具有抑癌功能。研究揭示了 LINE-1 通过逆转录转座激活 DNA 损伤检查点,影响基因组稳定性,从而抑制白血
, AMP, GTP, GDP, GMP and NAD+, for three human acute myelogenous leukemia (AML) cell lines, HL60, THP1, HEL [14-17], and one chronic myelogenous leukemia (CML) cell line, K562 [18]. All the measurements were made using the HPLC method [19].MATERIALS
α response, we used two human-tumor-derived cell lines: the melanoma line ME-15 (10 ) and the hepatoma line HuH7 (11 ). We have chosen these cell lines as models, because we have a good understanding of the IFNα responses at the mRNA and the protein levels











