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- 详细信息
- 文献和实验
- 技术资料
- 保质期:
12个月
- 供应商:
广州华韵生物科技有限公司
- 应用范围:
FCM
- 规格:
25μg
请联系华韵客服获取说明书。
产品简介:
| Background |
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
|
| Alternate Names |
LCA; Ly-5; T200;Leukocyte common antigen;Ptprc;Receptor-type tyrosine-protein phosphatase C
|
| Swissprot |
P04157
|
| Gene ID |
19265
|
| Clone No |
OX-1
|
| Host |
Mouse
|
| Reactivity |
Rat
|
| Application |
FCM
|
| Isotype |
Mouse IgG1, κ
|
| Isotype Control |
APC Mouse IgG1, κ Isotype Control[MOPC-21]
|
| Conjugation |
APC
|
| Conjugation Information |
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
|
| Spectrum |
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验, axin, and the tumor suppressor, adenomatouspolyposis coli (APC) protein (3) . In the absence of Wnt signaling,GSK-3 targets b-catenin for ubiquitin-mediated proteosomaldegradation by phosphorylation of b-catenin, axin, and APC (3) . Phosphorylation
v468 Chapter 6 细胞内结肠腺瘤样息肉蛋白核定位以及细胞质检测
7.6, and 1.37 MNaCl. Store at room temperature. 2. TBS with Tween (TBS-T) (10×): prepare a TBS solution (X1)and add 0.1% (v/v) Tween-20. 3. 5% (w/v) Non-fat dry milk in TBS-T. 4. Primary antibody: APC (Ab-1) antibody from OncogeneResearch.
1200/1800 L0109 Mouse anti-Human CD45 mAb,APC 50T/100T 1000/1500 L0110 Mouse anti-Human CD45 mAb,Biotin 50T/100T 800/1200 L0111
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