流式抗体/ AF/LE Purified Anti-Huma

CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

GPSAT;GYPA;HGpMiX;MNS;PAS2

P10747

940

CD28.2

Mouse

Human

FCM;Activ

Mouse IgG1, κ

AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]

None (AF/LE)

0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

冰袋